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Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia
Histone deacetylases (HDACs) are a key component of the epigenetic machinery regulating gene expression, and behave as oncogenes in several cancer types, spurring the development of HDAC inhibitors (HDACi) as anticancer drugs. This review discusses new results regarding the role of HDACs in cancer a...
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| 出版年: | Br J Cancer |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800301/ https://ncbi.nlm.nih.gov/pubmed/26908329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.36 |
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