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Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening

The rodent neuroblastoma cell line, ND7-23, is used to express voltage-dependent sodium (Nav) and other neuronal ion channels resistant to heterologous expression in Chinese hamster ovary (CHO) or human embryonic kidney (HEK) cells. Their advantage is that they provide endogenous factors and signali...

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Detalhes bibliográficos
Publicado no:Assay Drug Dev Technol
Main Authors: Rogers, Marc, Zidar, Nace, Kikelj, Danijel, Kirby, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800267/
https://ncbi.nlm.nih.gov/pubmed/26991361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2016.704
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