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Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug-binding site
Serum albumin (SA) is the main transporter of drugs in mammalian blood plasma. Here, we report the first crystal structure of equine serum albumin (ESA) in complex with antihistamine drug cetirizine at a resolution of 2.1 Å. Cetirizine is bound in two sites – a novel drug binding site (CBS1) and the...
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| Publicado no: | Mol Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800003/ https://ncbi.nlm.nih.gov/pubmed/26896718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.02.003 |
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