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Testosterone meets albumin – the molecular mechanism of sex hormone transport by serum albumins

Serum albumin is the most abundant protein in mammalian blood plasma and is responsible for the transport of metals, drugs, and various metabolites, including hormones. We report the first albumin structure in complex with testosterone, the primary male sex hormone. Testosterone is bound in two site...

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Publicado en:Chem Sci
Main Authors: Czub, Mateusz P., Venkataramany, Barat S., Majorek, Karolina A., Handing, Katarzyna B., Porebski, Przemyslaw J., Beeram, Sandya R., Suh, Kyungah, Woolfork, Ashley G., Hage, David S., Shabalin, Ivan G., Minor, Wladek
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371759/
https://ncbi.nlm.nih.gov/pubmed/30842823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04397c
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