Testosterone meets albumin – the molecular mechanism of sex hormone transport by serum albumins

Serum albumin is the most abundant protein in mammalian blood plasma and is responsible for the transport of metals, drugs, and various metabolites, including hormones. We report the first albumin structure in complex with testosterone, the primary male sex hormone. Testosterone is bound in two site...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Czub, Mateusz P., Venkataramany, Barat S., Majorek, Karolina A., Handing, Katarzyna B., Porebski, Przemyslaw J., Beeram, Sandya R., Suh, Kyungah, Woolfork, Ashley G., Hage, David S., Shabalin, Ivan G., Minor, Wladek
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371759/
https://ncbi.nlm.nih.gov/pubmed/30842823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04397c
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