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A 5′‐upstream short open reading frame encoded peptide regulates angiotensin type 1a receptor production and signalling via the β‐arrestin pathway

AUG sequences and short open reading frames are commonly present in the 5′‐leader sequence of G protein‐coupled receptor mRNAs. The presence of these upstream AUG sequences has been demonstrated to inhibit downstream receptor translation efficiency and, most recently, receptor signal transduction. A...

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Pubblicato in:J Physiol
Autori principali: Yosten, Gina L.C., Liu, Jun, Ji, Hong, Sandberg, Kathryn, Speth, Robert, Samson, Willis K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799972/
https://ncbi.nlm.nih.gov/pubmed/26333095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270567
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