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Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides
BACKGROUND: Approximately 40% of mammalian mRNA sequences contain AUG trinucleotides upstream of the main coding sequence, with a quarter of these AUGs demarcating open reading frames of 20 or more codons. In order to investigate whether these open reading frames may encode functional peptides, we h...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1402274/ https://ncbi.nlm.nih.gov/pubmed/16438715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-16 |
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