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Selective inhibition of angiotensin receptor signaling through Erk1/2 pathway by a novel peptide
A seven-amino acid peptide (PEP7) is encoded within a short open reading frame within exon 2 (E2) in the 5′-leader sequence (5′LS) upstream of the rat ANG 1a-receptor (rAT(1a)R) mRNA. A chemically synthesized PEP7 markedly inhibited ANG II-induced Erk1/2 activation in cell culture by 62% compared wi...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043133/ https://ncbi.nlm.nih.gov/pubmed/24523339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00562.2013 |
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