Selective inhibition of angiotensin receptor signaling through Erk1/2 pathway by a novel peptide

A seven-amino acid peptide (PEP7) is encoded within a short open reading frame within exon 2 (E2) in the 5′-leader sequence (5′LS) upstream of the rat ANG 1a-receptor (rAT(1a)R) mRNA. A chemically synthesized PEP7 markedly inhibited ANG II-induced Erk1/2 activation in cell culture by 62% compared wi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Jun, Yosten, Gina L. C., Ji, Hong, Zhang, Dan, Zheng, Wei, Speth, Robert C., Samson, Willis K., Sandberg, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Fluid and Electrolyte Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043133/
https://ncbi.nlm.nih.gov/pubmed/24523339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00562.2013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados