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Population pharmacokinetics of tanezumab in phase 3 clinical trials for osteoarthritis pain
AIMS: The aims were to 1) develop the pharmacokinetics model to describe and predict observed tanezumab concentrations over time, 2) test possible covariate parameter relationships that could influence clearance and distribution and 3) assess the impact of fixed dosing vs. a dosing regimen adjusted...
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| Udgivet i: | Br J Clin Pharmacol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4799925/ https://ncbi.nlm.nih.gov/pubmed/26613544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12850 |
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