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Shortened intervals during heterologous boosting preserve memory CD8 T cell function but compromise longevity
Developing vaccine strategies to generate high numbers of Ag-specific CD8 T cells may be necessary for protection against recalcitrant pathogens. Heterologous prime-boost-boost (HPBB) immunization has been shown to result in large quantities of functional memory CD8 T cells with protective capacitie...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4799748/ https://ncbi.nlm.nih.gov/pubmed/26903479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501797 |
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