Bistability of a coupled Aurora B kinase-phosphatase system in cell division

Aurora B kinase, a key regulator of cell division, localizes to specific cellular locations, but the regulatory mechanisms responsible for phosphorylation of substrates located remotely from kinase enrichment sites are unclear. Here, we provide evidence that this activity at a distance depends on bo...

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Udgivet i:eLife
Main Authors: Zaytsev, Anatoly V, Segura-Peña, Dario, Godzi, Maxim, Calderon, Abram, Ballister, Edward R, Stamatov, Rumen, Mayo, Alyssa M, Peterson, Laura, Black, Ben E, Ataullakhanov, Fazly I, Lampson, Michael A, Grishchuk, Ekaterina L
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798973/
https://ncbi.nlm.nih.gov/pubmed/26765564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10644
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