Bistability of a coupled Aurora B kinase-phosphatase system in cell division

Aurora B kinase, a key regulator of cell division, localizes to specific cellular locations, but the regulatory mechanisms responsible for phosphorylation of substrates located remotely from kinase enrichment sites are unclear. Here, we provide evidence that this activity at a distance depends on bo...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Zaytsev, Anatoly V, Segura-Peña, Dario, Godzi, Maxim, Calderon, Abram, Ballister, Edward R, Stamatov, Rumen, Mayo, Alyssa M, Peterson, Laura, Black, Ben E, Ataullakhanov, Fazly I, Lampson, Michael A, Grishchuk, Ekaterina L
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798973/
https://ncbi.nlm.nih.gov/pubmed/26765564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10644
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