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Further support for aneuploidy tolerance in wild yeast and effects of dosage compensation on gene copy-number evolution

In our prior work by Hose et al., we performed a genome-sequencing survey and reported that aneuploidy was frequently observed in wild strains of S. cerevisiae. We also profiled transcriptome abundance in naturally aneuploid isolates compared to isogenic euploid controls and found that 10–30% of amp...

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Veröffentlicht in:eLife
Hauptverfasser: Gasch, Audrey P, Hose, James, Newton, Michael A, Sardi, Maria, Yong, Mun, Wang, Zhishi
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798956/
https://ncbi.nlm.nih.gov/pubmed/26949252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14409
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