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Dosage compensation can buffer copy-number variation in wild yeast

Aneuploidy is linked to myriad diseases but also facilitates organismal evolution. It remains unclear how cells overcome the deleterious effects of aneuploidy until new phenotypes evolve. Although laboratory strains are extremely sensitive to aneuploidy, we show here that aneuploidy is common in wil...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hose, James, Yong, Chris Mun, Sardi, Maria, Wang, Zhishi, Newton, Michael A, Gasch, Audrey P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448642/
https://ncbi.nlm.nih.gov/pubmed/25955966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05462
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