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Excitatory transmission onto AgRP neurons is regulated by cJun NH(2)-terminal kinase 3 in response to metabolic stress

The cJun NH(2)-terminal kinase (JNK) signaling pathway is implicated in the response to metabolic stress. Indeed, it is established that the ubiquitously expressed JNK1 and JNK2 isoforms regulate energy expenditure and insulin resistance. However, the role of the neuron-specific isoform JNK3 is uncl...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vernia, Santiago, Morel, Caroline, Madara, Joseph C, Cavanagh-Kyros, Julie, Barrett, Tamera, Chase, Kathryn, Kennedy, Norman J, Jung, Dae Young, Kim, Jason K, Aronin, Neil, Flavell, Richard A, Lowell, Bradford B, Davis, Roger J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798947/
https://ncbi.nlm.nih.gov/pubmed/26910012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10031
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