Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone

AgRP neuron activity drives feeding and weight gain while that of nearby POMC neurons does the opposite. However, the role of excitatory glutamatergic input in controlling these neurons is unknown. To address this question, we generated mice lacking NMDA receptors (NMDARs) on either AgRP or POMC neu...

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Hlavní autoři: Liu, Tiemin, Kong, Dong, Shah, Bhavik P., Ye, Chianping, Koda, Shuichi, Saunders, Arpiar, Ding, Jun B., Yang, Zongfang, Sabatini, Bernardo L., Lowell, Bradford B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278709/
https://ncbi.nlm.nih.gov/pubmed/22325203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.11.027
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