Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone

AgRP neuron activity drives feeding and weight gain while that of nearby POMC neurons does the opposite. However, the role of excitatory glutamatergic input in controlling these neurons is unknown. To address this question, we generated mice lacking NMDA receptors (NMDARs) on either AgRP or POMC neu...

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Main Authors: Liu, Tiemin, Kong, Dong, Shah, Bhavik P., Ye, Chianping, Koda, Shuichi, Saunders, Arpiar, Ding, Jun B., Yang, Zongfang, Sabatini, Bernardo L., Lowell, Bradford B.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278709/
https://ncbi.nlm.nih.gov/pubmed/22325203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.11.027
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