Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord

Neuromyelitis optica (NMO) is an acute inflammatory disease of the central nervous system (CNS) which predominantly affects spinal cord and optic nerves. Most patients harbor pathogenic autoantibodies, the so-called NMO-IgGs, which are directed against the water channel aquaporin 4 (AQP4) on astrocy...

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Vydáno v:PLoS One
Hlavní autoři: Oji, Satoru, Nicolussi, Eva-Maria, Kaufmann, Nathalie, Zeka, Bleranda, Schanda, Kathrin, Fujihara, Kazuo, Illes, Zsolt, Dahle, Charlotte, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798752/
https://ncbi.nlm.nih.gov/pubmed/26990978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151244
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