Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord

Neuromyelitis optica (NMO) is an acute inflammatory disease of the central nervous system (CNS) which predominantly affects spinal cord and optic nerves. Most patients harbor pathogenic autoantibodies, the so-called NMO-IgGs, which are directed against the water channel aquaporin 4 (AQP4) on astrocy...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Oji, Satoru, Nicolussi, Eva-Maria, Kaufmann, Nathalie, Zeka, Bleranda, Schanda, Kathrin, Fujihara, Kazuo, Illes, Zsolt, Dahle, Charlotte, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798752/
https://ncbi.nlm.nih.gov/pubmed/26990978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151244
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