Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer

Therapies targeting the type I insulin-like growth factor receptor (IGF-1R) have not been developed with predictive biomarkers to identify tumors with receptor activation. We have previously shown that the insulin receptor substrate (IRS) adaptor proteins are necessary for linking IGF1R to downstrea...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Becker, Marc A., Ibrahim, Yasir H., Oh, Annabell S., Fagan, Dedra H., Byron, Sara A., Sarver, Aaron L., Lee, Adrian V., Shaw, Leslie M., Fan, Cheng, Perou, Charles M., Yee, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798554/
https://ncbi.nlm.nih.gov/pubmed/26991655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150564
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