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Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer

Therapies targeting the type I insulin-like growth factor receptor (IGF-1R) have not been developed with predictive biomarkers to identify tumors with receptor activation. We have previously shown that the insulin receptor substrate (IRS) adaptor proteins are necessary for linking IGF1R to downstrea...

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發表在:PLoS One
Main Authors: Becker, Marc A., Ibrahim, Yasir H., Oh, Annabell S., Fagan, Dedra H., Byron, Sara A., Sarver, Aaron L., Lee, Adrian V., Shaw, Leslie M., Fan, Cheng, Perou, Charles M., Yee, Douglas
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798554/
https://ncbi.nlm.nih.gov/pubmed/26991655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150564
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