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Hydroxyl PAMAM dendrimer-based gene vectors for transgene delivery to human retinal pigment epithelial cells()

Ocular gene therapy holds promise for the treatment of numerous blinding disorders. Despite the significant progress in the field of viral and non-viral gene delivery to the eye, significant obstacles remain in the way of achieving high-level transgene expression without adverse effects. The retinal...

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Detalhes bibliográficos
Publicado no:Nanoscale
Main Authors: Mastorakos, Panagiotis, Kambhampati, Siva P., Mishra, Manoj K., Wu, Tony, Song, Eric, Hanes, Justin, Kannan, Rangaramanujam M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797994/
https://ncbi.nlm.nih.gov/pubmed/25213606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4nr04284k
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