Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture

Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable physicochemical features, making them promising candidates for targeted drug delivery in the central nervous system (CNS). Systemically administered dendrimers have been shown to localize in activated glial cells, which...

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Udgivet i:Molecules
Main Authors: Alnasser, Yossef, Kambhampati, Siva P., Nance, Elizabeth, Rajbhandari, Labchan, Shrestha, Shiva, Venkatesan, Arun, Kannan, Rangaramanujam M., Kannan, Sujatha
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102539/
https://ncbi.nlm.nih.gov/pubmed/29702566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051025
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