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The metabolic phenotype of rodent sepsis: cause for concern?

PURPOSE: Rodent models of sepsis are frequently used to investigate pathophysiological mechanisms and to evaluate putative therapeutic strategies. However, preclinical efficacy in these models has failed to translate to the clinical setting. We thus questioned the representativeness of such models a...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Zolfaghari, Parjam S, Pinto, Bernardo Bollen, Dyson, Alex, Singer, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797805/
https://ncbi.nlm.nih.gov/pubmed/26266794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2197-425X-1-6
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