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The metabolic phenotype of rodent sepsis: cause for concern?

PURPOSE: Rodent models of sepsis are frequently used to investigate pathophysiological mechanisms and to evaluate putative therapeutic strategies. However, preclinical efficacy in these models has failed to translate to the clinical setting. We thus questioned the representativeness of such models a...

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Vydáno v:Intensive Care Med Exp
Hlavní autoři: Zolfaghari, Parjam S, Pinto, Bernardo Bollen, Dyson, Alex, Singer, Mervyn
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797805/
https://ncbi.nlm.nih.gov/pubmed/26266794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2197-425X-1-6
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