Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency

T lymphocytes are essential mediators of immunity that are produced by the thymus in proportion to its size. The thymus atrophies rapidly with age, resulting in progressive diminution of new T cell production. This decreased output is compensated by duplication of existing T cells, but it results in...

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Udgivet i:Cell Rep
Main Authors: Griffith, Ann V, Venables, Thomas, Shi, Jianjun, Farr, Andrew, van Remmen, Holly, Szweda, Luke, Fallahi, Mohammad, Rabinovitch, Peter, Petrie, Howard T.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797338/
https://ncbi.nlm.nih.gov/pubmed/26257169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.008
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