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Scrambled Prion Domains Form Prions and Amyloid

The [URE3] prion of Saccharomyces cerevisiae is a self-propagating amyloid form of Ure2p. The amino-terminal prion domain of Ure2p is necessary and sufficient for prion formation and has a high glutamine (Q) and asparagine (N) content. Such Q/N-rich domains are found in two other yeast prion protein...

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Autors principals: Ross, Eric D., Baxa, Ulrich, Wickner, Reed B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC479727/
https://ncbi.nlm.nih.gov/pubmed/15282319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7206-7213.2004
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