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Prion generation in vitro: amyloid of Ure2p is infectious

[URE3] is a prion (infectious protein) of the Ure2 protein of yeast. In vitro, Ure2p can form amyloid filaments, but direct evidence that these filaments constitute the infectious form is still missing. Here we demonstrate that recombinant Ure2p converted into amyloid can infect yeast cells lacking...

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Hlavní autoři: Brachmann, Andreas, Baxa, Ulrich, Wickner, Reed Brendon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201353/
https://ncbi.nlm.nih.gov/pubmed/16096644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600772
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