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Human Umbilical Vein Endothelial Cells foster conversion of CD4(+)CD25(−)Foxp3(−) T cells into CD4(+)Foxp3(+) Regulatory T Cells via Transforming Growth Factor-β

Trans-placental cell trafficking is a naturally occurring process during pregnancy that results in the direct recognition of foreign maternal antigens by fetal tissue and vice versa. Immigration of potentially harmful allo-reactive maternal T cells into fetal circulation may provoke anti-fetal immun...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Oettel, Anika, Lorenz, Mario, Stangl, Verena, Costa, Serban-Dan, Zenclussen, Ana Claudia, Schumacher, Anne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796866/
https://ncbi.nlm.nih.gov/pubmed/26987775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23278
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