Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

A neuropathological hallmark of Alzheimer disease (AD) is a widespread amyloid deposition. We analyzed the entire amino acid sequences in an amyloid preparation and found, in addition to the major beta/A4-protein (A beta) fragment, two unknown peptides. We raised antibodies against synthetic peptide...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Uéda, K, Fukushima, H, Masliah, E, Xia, Y, Iwai, A, Yoshimoto, M, Otero, D A, Kondo, J, Ihara, Y, Saitoh, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11282
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