Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.
A neuropathological hallmark of Alzheimer disease (AD) is a widespread amyloid deposition. We analyzed the entire amino acid sequences in an amyloid preparation and found, in addition to the major beta/A4-protein (A beta) fragment, two unknown peptides. We raised antibodies against synthetic peptide...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11282 |
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