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Metal-free intermolecular formal cycloadditions enable an orthogonal access to nitrogen heterocycles

Nitrogen-containing heteroaromatic cores are ubiquitous building blocks in organic chemistry. Herein, we present a family of metal-free intermolecular formal cycloaddition reactions that enable highly selective and orthogonal access to isoquinolines and pyrimidines at will. Applications of the produ...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Xie, Lan-Gui, Niyomchon, Supaporn, Mota, Antonio J., González, Leticia, Maulide, Nuno
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796318/
https://ncbi.nlm.nih.gov/pubmed/26975182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10914
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