Repeated administration of low-dose cisplatin in mice induces fibrosis

Cisplatin, a chemotherapeutic used for the treatment of solid cancers, has nephrotoxic side effects leading to acute kidney injury (AKI). Cisplatin cannot be given to patients that have comorbidities that predispose them to an increased risk for AKI. Even without these comorbidities, 30% of patients...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Sharp, Cierra N., Doll, Mark A., Dupre, Tess V., Shah, Parag P., Subathra, Marimuthu, Siow, Deanna, Arteel, Gavin E., Megyesi, Judit, Beverly, Levi J., Siskind, Leah J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796272/
https://ncbi.nlm.nih.gov/pubmed/26739893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00512.2015
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