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Repeated administration of low-dose cisplatin in mice induces fibrosis

Cisplatin, a chemotherapeutic used for the treatment of solid cancers, has nephrotoxic side effects leading to acute kidney injury (AKI). Cisplatin cannot be given to patients that have comorbidities that predispose them to an increased risk for AKI. Even without these comorbidities, 30% of patients...

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Dettagli Bibliografici
Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Sharp, Cierra N., Doll, Mark A., Dupre, Tess V., Shah, Parag P., Subathra, Marimuthu, Siow, Deanna, Arteel, Gavin E., Megyesi, Judit, Beverly, Levi J., Siskind, Leah J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796272/
https://ncbi.nlm.nih.gov/pubmed/26739893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00512.2015
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