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Moderate aging does not exacerbate cisplatin-induced kidney injury or fibrosis despite altered inflammatory cytokine expression and immune cell infiltration

Aging is a risk factor for certain forms of kidney injury due to normal physiological changes, but the role of aging in cisplatin-induced kidney injury is not well defined in humans or animal models of the disease. To improve on current knowledge in this field, we treated 8- and 40-wk-old FVB/n mice...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Sharp, Cierra N., Doll, Mark, Dupre, Tess V., Beverly, Levi J., Siskind, Leah J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383196/
https://ncbi.nlm.nih.gov/pubmed/30484347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00463.2018
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