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De novo identification of replication-timing domains in the human genome by deep learning
Motivation: The de novo identification of the initiation and termination zones—regions that replicate earlier or later than their upstream and downstream neighbours, respectively—remains a key challenge in DNA replication. Results: Building on advances in deep learning, we developed a novel hybrid a...
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| Pubblicato in: | Bioinformatics |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4795613/ https://ncbi.nlm.nih.gov/pubmed/26545821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv643 |
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