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Methylnaltrexone for opioid-induced constipation: review and meta-analyses for objective plus subjective efficacy and safety outcomes

INTRODUCTION: Opioid-induced constipation (OIC) is a frequent adverse event that impairs patients’ quality of life. This article evaluates the objective plus subjective efficacy and the safety of methylnaltrexone (MNTX) in OIC patients. METHODS: Randomized controlled trials from a recent systematic...

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Bibliografiske detaljer
Udgivet i:Ther Clin Risk Manag
Main Authors: Siemens, Waldemar, Becker, Gerhild
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795449/
https://ncbi.nlm.nih.gov/pubmed/27042082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S80749
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