A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses

BACKGROUND: NF-κB is widely involved in lymphoid malignancies; however, the functional roles and specific transcriptomes of NF-κB dimers with distinct subunit compositions have been unclear. METHODS: Using combined ChIP-sequencing and microarray analyses, we determined the cistromes and target gene...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Med
Main Authors: de Oliveira, Kivia A. P., Kaergel, Eva, Heinig, Matthias, Fontaine, Jean-Fred, Patone, Giannino, Muro, Enrique M., Mathas, Stephan, Hummel, Michael, Andrade-Navarro, Miguel A., Hübner, Norbert, Scheidereit, Claus
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794921/
https://ncbi.nlm.nih.gov/pubmed/26988706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0280-5
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