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Lymphotoxin and lipopolysaccharide induce NF-κB-p52 generation by a co-translational mechanism

The 'classical' NF-κB activation pathway proceeds via IκB kinase (IKK)-β/γ-mediated phosphorylation, induced ubiquitination and the degradation of small IκBs. An alternative, NF-κB-inducing kinase and IKK-α-dependent pathway, which stimulates the processing of NF-κB2/p100, has recently bee...

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Hlavní autoři: Mordmüller, Benjamin, Krappmann, Daniel, Esen, Meral, Wegener, Elmar, Scheidereit, Claus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315810/
https://ncbi.nlm.nih.gov/pubmed/12524526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor710
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