Inhibition of Src homology 2 domain‐containing phosphatase 1 increases insulin sensitivity in high‐fat diet‐induced insulin‐resistant mice

Insulin resistance plays a crucial role in the development of type 2 diabetes. Insulin receptor signalling is antagonized and tightly controlled by protein tyrosine phosphatases (PTPs). However, the precise role of the PTP src homology 2 domain‐containing phosphatase 1 (SHP‐1) in insulin resistance...

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Publicado en:FEBS Open Bio
Autores principales: Krüger, Janine, Wellnhofer, Ernst, Meyborg, Heike, Stawowy, Philipp, Östman, Arne, Kintscher, Ulrich, Kappert, Kai
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794785/
https://ncbi.nlm.nih.gov/pubmed/27047746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12000
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