Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice

OBJECTIVE: Insulin resistance can be triggered by enhanced dephosphorylation of the insulin receptor or downstream components in the insulin signaling cascade through protein tyrosine phosphatases (PTPs). Downregulating density-enhanced phosphatase-1 (DEP-1) resulted in an improved metabolic status...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Krüger, Janine, Brachs, Sebastian, Trappiel, Manuela, Kintscher, Ulrich, Meyborg, Heike, Wellnhofer, Ernst, Thöne-Reineke, Christa, Stawowy, Philipp, Östman, Arne, Birkenfeld, Andreas L., Böhmer, Frank D., Kappert, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354926/
https://ncbi.nlm.nih.gov/pubmed/25830095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.02.001
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