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Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor.

Activation of T lymphocytes requires the recognition of peptide-major histocompatibility complex complexes and costimulatory signals provided by antigen-presenting cells (APCs). The best-characterized costimulatory molecule to date is the B7 antigen, a member of the immunoglobulin family that binds...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Razi-Wolf, Z, Galvin, F, Gray, G, Reiser, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504299/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11182
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