Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor.
Activation of T lymphocytes requires the recognition of peptide-major histocompatibility complex complexes and costimulatory signals provided by antigen-presenting cells (APCs). The best-characterized costimulatory molecule to date is the B7 antigen, a member of the immunoglobulin family that binds...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1993
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504299/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11182 |
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