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CTLA4 mediates antigen-specific apoptosis of human T cells.

The regulation of T cell-mediated immune responses requires a balance between amplification and generation of effector function and subsequent selective termination by clonal deletion. Although apoptosis of previously activated T cells can be induced by signaling of the tumor necrosis factor recepto...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Gribben, J G, Freeman, G J, Boussiotis, V A, Rennert, P, Jellis, C L, Greenfield, E, Barber, M, Restivo, V A, Ke, X, Gray, G S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.811
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