MCPIP1 selectively destabilizes transcripts associated with an anti-apoptotic gene expression program in breast cancer cells that can elicit complete tumor regression

The ability of cancer cells to evade apoptosis is dictated by a shift in the balance between pro- and anti-apoptotic gene expression programs. Monocyte chemotactic protein induced protein 1 (MCPIP1) is a zinc finger RNA binding protein with important roles in mediating inflammatory responses. Overex...

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Foilsithe in:Cancer Res
Main Authors: Lu, Wenbao, Ning, Huan, Gu, Ling, Peng, Hui, Wang, Qinghong, Hou, Rong, Fu, Mingui, Hoft, Daniel F., Liu, Jianguo
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794406/
https://ncbi.nlm.nih.gov/pubmed/26833120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1115
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