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Transcriptional regulation of miR-31 by oncogenic KRAS mediates metastatic phenotypes by repressing RASA1
Activating KRAS mutations are nearly ubiquitous in pancreatic cancer occurring in more than 95% of clinical cases. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding sequences within the 3′UTRs of target mRNAs. An integral role for miRNAs in cancer pathogenesis is...
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794362/ https://ncbi.nlm.nih.gov/pubmed/26747707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0456 |
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