Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma

To investigate the underlying causes of chemoresistance in malignant pleural mesothelioma, we have studied mesothelioma cell lines as 3D spheroids, which acquire increased chemoresistance compared to 2D monolayers. We asked whether the gene expression of 3D spheroids would reveal mechanisms of resis...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Barbone, Dario, Van Dam, Loes, Follo, Carlo, Jithesh, Puthen V., Zhang, Shu-Dong, Richards, William G., Bueno, Raphael, Fennell, Dean A., Broaddus, V. Courtney
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794185/
https://ncbi.nlm.nih.gov/pubmed/26982031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150044
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