Demonstrating Functional Equivalence of Pilot and Production Scale Freeze-Drying of BCG

Process analytical technology (PAT)-tools were used to monitor freeze-drying of Bacille Calmette-Guérin (BCG) at pilot and production scale. Among the evaluated PAT-tools, there is the novel use of the vacuum valve open/close frequency for determining the endpoint of primary drying at production sca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: ten Have, R., Reubsaet, K., van Herpen, P., Kersten, G., Amorij, J.-P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794149/
https://ncbi.nlm.nih.gov/pubmed/26981867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151239
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