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Demonstrating Functional Equivalence of Pilot and Production Scale Freeze-Drying of BCG
Process analytical technology (PAT)-tools were used to monitor freeze-drying of Bacille Calmette-Guérin (BCG) at pilot and production scale. Among the evaluated PAT-tools, there is the novel use of the vacuum valve open/close frequency for determining the endpoint of primary drying at production sca...
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| Vydáno v: | PLoS One |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794149/ https://ncbi.nlm.nih.gov/pubmed/26981867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151239 |
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