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The Production of a Stable Infliximab Powder: The Evaluation of Spray and Freeze-Drying for Production
In prospect of developing an oral dosage form of Infliximab, for treatment of Crohn’s disease and rheumatoid arthritis, freeze-drying (vial vs Lyoguard trays) and spray-drying were investigated as production method for stable powders. Dextran and inulin were used in combination with sucrose as stabi...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5051734/ https://ncbi.nlm.nih.gov/pubmed/27706175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163109 |
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