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Simeprevir and Sofosbuvir Combination Treatment in a Patient with HCV Cirrhosis and HbS Beta 0-Thalassemia: Efficacy and Safety despite Baseline Hyperbilirubinemia

Hyperbilirubinemia is an adverse reaction of simeprevir (SMV). The majority of these patients were taking concurrent ribavirin presenting elevated unconjugated hyperbilirubinemia due to hemolysis. However, cases of hepatic failure with elevated bilirubin level have also been reported in patients wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Case Rep Hematol
Hauptverfasser: Papadopoulos, Nikolaos, Deutsch, Melanie, Georgalas, Athanasios, Poulakidas, Helias, Karnesis, Lazaros
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793097/
https://ncbi.nlm.nih.gov/pubmed/27042368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7635128
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