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Simeprevir and Sofosbuvir Combination Treatment in a Patient with HCV Cirrhosis and HbS Beta 0-Thalassemia: Efficacy and Safety despite Baseline Hyperbilirubinemia

Hyperbilirubinemia is an adverse reaction of simeprevir (SMV). The majority of these patients were taking concurrent ribavirin presenting elevated unconjugated hyperbilirubinemia due to hemolysis. However, cases of hepatic failure with elevated bilirubin level have also been reported in patients wit...

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Detalhes bibliográficos
Publicado no:Case Rep Hematol
Main Authors: Papadopoulos, Nikolaos, Deutsch, Melanie, Georgalas, Athanasios, Poulakidas, Helias, Karnesis, Lazaros
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793097/
https://ncbi.nlm.nih.gov/pubmed/27042368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7635128
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