IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

Dysregulated inflammasome activation contributes to respiratory infections and pathologic airway inflammation. Through basic and translational approaches involving murine models and human genetic epidemiology, we show here the importance of the different inflammasomes in regulating inflammatory resp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Iannitti, Rossana G., Napolioni, Valerio, Oikonomou, Vasilis, De Luca, Antonella, Galosi, Claudia, Pariano, Marilena, Massi-Benedetti, Cristina, Borghi, Monica, Puccetti, Matteo, Lucidi, Vincenzina, Colombo, Carla, Fiscarelli, Ersilia, Lass-Flörl, Cornelia, Majo, Fabio, Cariani, Lisa, Russo, Maria, Porcaro, Luigi, Ricciotti, Gabriella, Ellemunter, Helmut, Ratclif, Luigi, De Benedictis, Fernando Maria, Talesa, Vincenzo Nicola, Dinarello, Charles A., van de Veerdonk, Frank L., Romani, Luigina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793079/
https://ncbi.nlm.nih.gov/pubmed/26972847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10791
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