Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells

The tumor suppressor protein p53 is unstable in quiescent cells and undergoes proteosomal degradation. Under conditions of cellular stress, p53 is rapidly stabilized by post-translational modification, thereby escaping degradation and translocating to the nucleus where it activates genes related to...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Ahn, Hee-Jin, Kim, Kwang-Soo, Shin, Kyung-Won, Lim, Kee-Hwan, Kim, Jin-Ock, Lee, Je-Yong, Kim, Jiewan, Park, Ji-Hoon, Yang, Kyung-Min, Baek, Kwang-Hyun, Ko, Jeong-Jae, Park, Kyung-Soon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792573/
https://ncbi.nlm.nih.gov/pubmed/26540344
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